Thursday, August 14, 2014

Wartime Penicillin Drama : 3 non-chemists promote chemical penicillin while 3 working chemists promote natural penicillin ...

Three middle-aged chemist manques who disgracefully put youthful dreams before the public good - at the height of a total war


Three of wartime penicillin's chief protagonists were men who, as youths, had hoped to become hands-on lab research chemists but whom necessity had pushed them instead into becoming medical science desk administrators.

Their names ?

 Howard Florey, director of Oxford University's Dunn Path Institute , A. Newton Richards, head of the Medical Division of Vannevar Bush's famous OSRD war-science agency and George W. Merck , head of Merck.

All three greatly respected each other and worked as closely together as the American and British governments (nominally allies) allowed.

Wartime penicillin gave all three a second childhood as chemist manques and disgracefully, they ran with it* .

Even as a world at war panted instead for lots of disease-fighting drugs in any form , as long as they worked , were safe and were available NOW .

"Middle Aged Crazy"



For ten useless years (before , during and after WWII) they placed their highest priority on producing totally synthesized artificial (patentable) commercially viable penicillin.

They didn't get it and we still haven't.

If we had left penicillin just to them - as most at the top of the American and British governments had wanted  - we'd never seen any amount of penicillin . Not during the war and not for long after, until newly elected governments came to their senses , cut their losses and moved on.

Let us now honour the three chemists who put public good before their chosen profession


By pointed contrast , three working industrial chemists - men who had long struggled on the factory floor coming up with chemical solutions that reliably delivered safe, profitable, productive chemicals on time and on budget - saw naturally produced penicillin as the best solution.

The best solution perhaps for all time but certainly during a war emergency with its shortages of time and resources.

Let us now honour their names - as true patriots , as people who put the good of humanity before gaining more fame for their chosen profession.

These largely unknown and unhonoured heroes of the wartime penicillin saga made sure we had penicillin when it was most needed - D-Day and after.

And these three laid the groundwork for the kind of micro-biology technology that still produces all our antibiotics and many other medicines as well.

They are the American WPB's (War Production Board) Larry Elder ,  Glaxo chief Harry Jephcott and Pfizer chief John L Smith.

While we can show our disappointment for what Alexander Fleming, Florey , Martin Henry Dawson and all their co-workers did or didn't do with penicillin , it is my contention that all their actions were predictable , based on my through study of their personalities as displayed from youth on into middle age.

But I can't honestly say the same about Elder, Jephcott and Smith : they were the true wildcards of the whole wartime penicillin drama....

* I am mindful of former Nova Scotia premier John Buchanan who became a lawyer and a very very successful politician but who had really wanted to be a civil engineer.

Once in power, he drove the province into tremendous debt building anything and everything in sight : the once young engineer manque who finally got to 'drive the excavator'.

Most middle aged men - once they get money, a pot belly and grey hair - content themselves with finally buying the Corvette or Harley Davidson that Dad would never let them buy - but some (like Florey , Richards and Merck) do far more harm than that when they get a chance to go "middle aged crazy" .

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